Post Cycle Therapy

fit couple posing

One of the absolute worst side effects of using Androgenic and Anabolic Steroids (AAS) is the way it turns off your testosterone production.  Many athletes need to use post-cycle therapy to get their testosterone to come back up to pre-cycle levels.  This is the same basic approach that fertility clinics use to get infertile men to be able to father offspring.  

Like most bodybuilders, moderation is not something I’m fond of. So I found a three fold recipe which research has proven will cover the bases.  


Basic endocrinology of testosterone (T) production is actually pretty complicated. Most doctors don’t actually get it, even the ones prescribing Androgel and other HRT/TRT treatment.

In a healthy person it works like this: The pituitary receives a signal from gonadotropin releasing hormone (GTRH), which in turn causes the pituitary to release lutenizing hormone (LH) and follicle stimulating horomone (FSH).  These two hormones travel through the blood to your testes and each has a primary function. FSH causes sperm production to occur primarily, and LH causes Testosterone production to occur. Pretty simple right? This is where it gets hard; The body has several ways to shut down production if there is enough testosterone.  Testosterone is converted into other hormones called metabolites by two different enzymes.  5-alpha-reductase converts testosterone to dihydrotestosterone (DHT) and aromatase converts testosterone to estradiol (E2).  Both of these metabolites can bind to receptors on the pituitary that decrease testosterone production. They do the opposite of GTRH, they stop the release of LH and FSH.  

So when an athlete takes synthetic testosterone, either injectable or oral, most of it is broken down into DHT and E2. These shut off natural production of FSH and LH and results in the testicles shrinking as they no longer produce sperm or testosterone.  Now when you stop taking the AAS you no longer make your own FSH, LH, testosterone, or sperm.  

The Solution: Three Prong Assault

Prong #1

D-Aspardic Acid (DAA) has recently been shown to not benefit young healthy bodybuilders by raising their testosterone or strength, but in older men with decreased levels it works wonders!

 If you’re on or post cycle, you are in a self inflicted Andropause (male menopause), and thus your an ‘older male’ for purposes of this discussion.  3g of DAA on an empty stomach first thing in the morning works incredibly well and fast at increasing T levels, energy, and sex drive.  This is prong one; directly stimulate the testes to kick T production in right away.  

Prong #2

The second prong is to block the estrogen receptor on the pituitary, but not stimulate it. Like sticking gum in a lock so the key can’t bind.  This can be done with a Selective Estrogen Receptor Modulator (SERM). According to Greek researchers, when trying to determine which perscription SERM worked the best, they determined that Tamoxifen works better than it’s competitors.

All three compounds boosted LH and FSH and as a result Testosterone and Sperm production. The SERM binds to the estrogen receptor on the pituitary and stops estrogen from telling the pituitary not to make LH and FSH. This allows the GTRH to tell the pituitary to make LH and FSH.  This is proof that the entire class of SERMS can help with a post cycle athlete. In the case of Tamoxifen, it actually stimulated LH release directly, acting as an agonist not an antagonist. 

Prong #3

Aromatase inhibition is prong number three.  In a dutch study just once weekly dosing of Letrozole, a potent aromatase inhibitor, resulted in these results:

Total and Free testosterone quadrupled and the effects lasted for up to six months! Thats incredible! All aromatase inhibitors work on the same mechanism, they stop the aromatase enzyme from converting testosterone to estrogen.  

In a Turkish study it was discovered that daily dosing with Letrozole resulted in drastically increased sperm count and mobility.

Although in this study FSH and LH were not significantly increased.  And testosterone was not quadrupled, only doubled.  Perhaps once a week is better than once a day for purposes of boosting LH and FSH.  


The three prong assault causes the body to directly produce more testosterone from the DAA action on the testes, uses Aromatase inhibitors to stop aromatase from making estrogen from that newly produced testosterone, and uses SERMs to block the estrogen receptors so what estrogen is made can’t stop LH and FSH from being produced. This in turn causes long term testosterone production and recovers one from their previous cycle.  

While the SERMs tested and Letrozole are prescription drugs there are many effective non prescription products available that are SERMs and Aromatase inhibitors. 2 of which are combination products of SERMs and Aromatase Inhibitors; Form XT and Arom X.  I would use both together at half dose since they are made with completely different ingredients and the 2 together would work synergistically to increase testosterone and sperm production and get you back on track!  And dont forget to pick up some Rise and Swell. Rise and Swell is the DAA plus other cofactors like Vitamin D that you need to make testosterone.  The best legal PCT available is  Rise and Swell + Form XT and/or Arom X!

Nothing in this article or on this site should be considered medical advice or as an endorsement to violate any law of the country in which you reside.  The information given is for fun and entertainment purposes only.  All claims are 100% dependent upon proper diet and exercise.  Please consult a medical practitioner prior to any diet and exercise program.


Fertil Steril. 2009 Apr;91(4 Suppl):1427-30.

Eur J Endocrinol. 2008 May;158(5):741-7.

Fertil Steril. 2010 Oct 8. [Epub ahead of print]

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