The Mind - Page 4 of 15 - Mind And Muscle

A Brief History of the MAOIs The enzyme monoamine oxidase (MAO) is responsible for the destruction of various monoamine neurotransmitters including serotonin, noradrenaline, and dopamine. As humans age, levels of monoamine oxidase increase, reducing the availability of neurotransmitters and theoretically increasing the risk of disorders such as depression and Parkinson’s disease (10). Drugs that inhibit […]

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In Part I, we reviewed the theory, history, and overall pharmacology of l-deprenyl. Part II will discuss the possible applications of l-deprenyl, including its role as a neuroprotectant, antidepressant, and anti-addiction medication. But to continue where we left off last time is, as promised, let us first discuss l-deprenyl’s amphetamine metabolites. Amphetamine Metabolites L-deprenyl has […]

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Assuming you respond to Pergolide in a manner similar to how I do (and, luckily, the majority of users have been, to the point where I don’t feel like I’m the outlier giving all the advice…), your cycle will probably progress something like this: Week 1 – You get pill-poppin’ as per my instructions and […]

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Since the ’90s, popularity of the designer drug Ecstasy (MDMA) has soared, successfully securing a place in almost everyone’s recreational drug vocabulary. Millions of high school and college students worldwide have tried the drug. Much of Ecstasy’s popularity lies in its unique profile; instead of leaving the user stoned or drunk, MDMA can increase clarity […]

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Indicated for the treatment of depression and smoking cessation, bupropion (better known as Wellbutrin and Zyban) is sometimes used “off-label” for ADHD, weight loss, and even sexual dysfunction. Needless to say, this neat little compound has a few interesting properties that make it relevant to those interested in performance and physique enhancement. So without further […]

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 Hale’s Review by: Marc McDougal Lets get into estrogen…give us a rundown of receptor subtypes, some common misconceptions, and any other inside info you have. Well, as some background, there are 2 well characterized nuclear estrogen receptors: ERα and ERβ. These function as classic nuclear steroid receptors by binding to response elements in target genes and […]

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Stemming from the frequent observation that cigarette smokers tend to maintain lower body weights than their non-smoking counterparts, it is an intriguing idea that by using a nicotine product (such as a patch or gum), one could experience beneficial body composition effects while avoiding the carcinogenic dangers of cigarette smoke. In this issue of “Chemically […]

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