Best Prohormones of 2018 - Mind And Muscle

2017 saw a mild increase in the number of legal prohormones on the market but it also saw more of the illegal ones taken off the market. Prohormones are a popular category of sports supplements because they can give you better performance than standard testosterone boosting agents. Testosterone boosters only get the body’s levels to normal high, while prohormones can exceed what is naturally produced by the body and into higher than normal levels of androgens.

There are many prohormones on the market and they can be broken down into several categories. The first category is “wet” vs “dry” prohormones. On a typical cycle a man over 21 would want to take a ratio of 3:1 dry to wet prohormones. Dry means that there is no estrogen conversion and wet means that there is some estrogen conversion.

Estrogen isn’t a bad thing, it’s necessary for every body to function properly, so it’s not a good idea to push estrogen too low or there won’t be growth and you may experience some negative side effects. Estrogen at the ER beta is also critical for muscle growth, so it’s not a bad thing to have some estrogen in your cycle of prohormones.

The best prohormones are ones that meet your goals and this article will break down those goals for you and suggest a cycle to meet that goal.

Prohormones On The Market

  • 1-Androsterone (1-DHEA, 3-beta-hydroxy-androst-1-ene-17-one, 1-Androstene-3b-ol,17-one) – this is the most potent prohormone on the market for increasing the natural androgen “1-Testosterone”. 1-Test, unlike regular testosterone does not convert into estrogen and is 2-7 times more anabolic than standard testosterone. It is dry and will give you strength, fat loss and size when combined with a proper diet and exercise program. (report of size, strength and fat loss)
  • 4-Androsterone (4-DHEA, 3-beta-hydroxy-androst-4-ene-17-one, 4-Androstene-3b-ol,17-one) – this is a prohormone to standard testosterone. Testosterone is the body’s natural and most abundant anabolic steroid. It is used to gain mass and size while putting on strength to your lifts when you combine it with proper diet and exercise. (reports of mass gains)
  • 5-Androsterone (5-DHEA, 3-beta-hydroxy-androst-5-ene-17-one, 5-Androstene-3b-ol,17-one) – the worlds first prohormone 5-DHEA or often known as “DHEA” is a prohormone to testosterone and other androgens. This prohormone lowers cortisol and may help you cut fat while boosting testosterone levels. (reports of leaning out and strength)
  • Epiandrosterone (3-beta-hydroxy-androstane-17-one, Androstane-3b-ol,17-one) – this is a prohormone to Stanolone, which is the body’s dry steroid. Stanolone can cause hair loss issues for those that are prone, but it seems that Epiandrosterone does not share this effect in theory because much of the Stanolone created is in target tissues like fat and muscle. Epiandrosterone is best known for helping people cut and increase strength when combined with a proper diet and exercise program. (reports of strength gains and leaning out)
  • Androsterone (3-alpha-hydroxy-androstane-17-one, 1-Androstane-3a-ol,17-one) – the chemical isomer to Epiandrosterone, this one seems to be more active in muscle but does seem to cause more of a hair loss effect. Androsterone is also good for reducing estrogen in the body. (reports of strength and leaning out).
  • 6-Keto-Progesterone (6-keto-pregna-4-ene-3, 20-dione,17-one) – this is theorized to be a pure anabolic with no androgenic, estrogenic or progestational properties, which means it probably works on s similar pathway to ecdysterone and other plant based steroids. This compound can put on size and strength with no reported side effects. It is also theorized that it lowers myostatin levels in the body. It’s great to add to a cycle but is hard to find these days.
  • 5a-OHP (17beta-{1-Ketoethyl}-androstane-3-one, 17a-ol) – this is a prohormone to Stanolone but like Epiandrosterone also doesn’t seem to have the hair loss effects. This is a natural progestin which is theorized to lower myostatin levels and increase lean mass.
  • 1,4-OHP (17beta-{1-Ketoethyl}-androsta-1,4-diene-3-one, 17a-ol) – this is a prohormone to boldenone which has been reported to increase appetite and lubricate the joints. It’s not a major builder but is great to add to any cycle to help ease side effects and help you get in all of your macro calories.


There are some basic prohormone stacks that work well for a specific goal. You can also buy blends of prohormones where the manufacturers make their own blend. You can use these if you trust the manufacturers formulations. Many are good and some are bad. It depends on the company.

You can make a stack out of individual ingredients like the ones from Liquid Labs and other companies that make singular ingredient products or you can opt for the blends. It’s really a matter of personal choice.


Long gone, thankfully are the illegal methylated prohormones which are liver toxic and cause cardiovascular damage. Products like M-Stenbolone and Dymethazine are dangerous, illegal and without any basis to be sold as a dietary supplement. Also gone are most SARM products that are untested and also illegal to sell as dietary supplements. Unfortunately, many of the prohormones mentioned are hard to find and becoming scarce until Hi-Tech Pharmaceuticals starts producing them again.


Check out the “Basic Mass Stack” if you want to have prohormone gains in a complete cycle along with post cycle therapy.

If you want the most scientifically advanced way to boost testosterone, check out Rise and Swell from Liquid Labs. This super supplement promotes testosterone production on 5 key pathways. Other testosterone boosting agents promote only one pathway!

Stacking two potent preworkouts is essential to my day. I use Wyked from Liquid Labs to boost IGF-1 levels along with creatine levels. Stack it with Mesomorph from APS Nutrition. Wyked has caffeine and Yohimbine, while Mesomorph has evereything else stimulant based. Take Wyked 40 minutes prior to working out and Mesomorph immediately before you train.

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