Prohormones: Norandrostenedione

jacked guy liftingNorandrostenedione (19-nor-4-androsten-3, 17-dione) is a prohormone that was released before the 2004 prohormone ban. Norandrostenedione is converted to nandrolone (“deca”) via the enzyme 17-beta-hydroxysteroid dehydrogenase (17bHSD). Norandrostenedione is similar in effect to norandrostenediol, but norandrostenedione is more androgenic with an anabolic to androgenic ratio of 37/55.

Norandrostenedione does convert to estrogen, but not as much as the other prohormones available around the same time like androstenedione and androstenediol. The estrogenic effects of prohormones in combination with their low conversion rate to the target hormone can be a problem because large amounts need to be taken to see results, and much of the prohormone ends up being converted to estrogen. This can easily cause estrogenic side effects such as gynecomastia. Androgenic side effects are more of a possibility with norandrostenedione than with norandrostenediol due to its increased androgenic activity. Norandrostenedione is not C-17 methylated, so it should not cause the large amounts of liver stress that many other prohormones do.

Like other prohormones, the effectiveness of norandrostenedione is limited by its short half-life and low oral bioavailability. Large frequent doses need to be taken to see results, typically 800mg/day or more. Taking norandrostenedione with a fat containing meal can help increase absorption as norandrostenedione is not a C-17 methylated prohormone.

Noradrostenedione is considered to be stronger in terms of strength and muscle building than most of the other pre-ban prohormones, and also milder in terms of side effects. Norandrostenedione is not longer available as it was included in the Anabolic Steroid Control Act of 2004, and was banned as of January 20th, 2005.While Norandrostenediol is no longer available, norDHEA (Norandrostene-3b-Ol, 17-One) is still completely legal and available over the counter. NorDHEA converts to nandrolone in a 2-step process, so it may produce similar effects to norandrostenedione.

To view 100% legal and effective prohormones including norDHEA (Norandrostene-3b-Ol, 17-One), click here.


1. Roberts, S (2009). Anabolic Pharmacology.

2. Parr MK, Laudenbach-Leschowsky U, Höfer N, Schänzer W, & Diel P. (2009). Anabolic and androgenic activity of 19-norandrostenedione after oral and subcutaneous administration–analysis of side effects and metabolism. Toxicology Letters. 188(2), 137-41.

3. Broeder CE. (2003). Oral andro-related prohormone supplementation: do the potential risks outweigh the benefits? Canadian Journal of Applied Physiology = Revue Canadienne De Physiologie Appliquée. 28(1), 102-16.

4. Ziegenfuss TN, Berardi JM, & Lowery LM. (2002). Effects of prohormone supplementation in humans: a review. Canadian Journal of Applied Physiology = Revue Canadienne De Physiologie Appliquée. 27(6), 628-46.

5. Colker CM, Antonio J, & Kalman D. (2001). The metabolism of orally ingested 19-nor-4-androstene-3,17-dione and 19-nor-4-androstene-3,17-diol in healthy, resistance-trained men. Journal of Strength and Conditioning Research / National Strength & Conditioning Association. 15(1), 144-7.

6. Raeside JI, Renaud RL, & Friendship RM. (1989). Aromatization of 19-norandrogens by porcine Leydig cells. Journal of Steroid Biochemistry. 32(5), 729-35.

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