T2 Supplementation for Fat Loss
The sport of bodybuilding is known for utilizing various types of physiological boosters to increase muscle mass and to decrease fat to achieve the desired aesthetic look. In most cases, the human body already produces these substances in moderation (e.g. testosterone), but adding to the regular production helps elicit more noticeable changes. One of these substances is T2 (diiodothyronines), a type of thyroid hormone produced by the thyroid gland.
The thyroid gland is responsible for various components of growth and maturation, heart and brain function, bone density, muscle control, and what we, bodybuilding athletes, care about most, your metabolic rate. Controlling these actions release one of two main hormones: (a) thyroxine (T4), whose primary role is to lower the role of the more active thyroid hormone (T3), and (b) triiodothyronine (T3), which is responsible for regulating those various body functions mentioned above. Since T3 helps regulate metabolic functions, an under production may lead to weight gain because of hypothyroidism, while an overproduction leads to weight loss as a result of hyperthyroidism, making it an attractive supplement for bodybuilders in their prep season. While fat loss is desirable to bodybuilders, some of the other symptoms associated with hyperthyroidism may not be (i.e. anxiety, irritability, overproduction of heat, menstrual irregularities, nervousness, hyperactivity, and catabolism), reducing its attractiveness to athletes. However, scientists have found a way around the undesired catabolic side effect associated with hyperthyroidism due to an over production (or supplementation) of T3.
3,5-Diiodo-L-Thyronine (T2) is a derivative of T3 that exhibits similar metabolic effects to that of T3, without all the other negative side effects. T3 and T4 supplementation shut down the thyroid’s natural thyroid hormone production, which produces a catabolic effect on the muscle tissues. T2, on the other hand, while it acts similarly to T3, it does not shut down the body’s natural thyroid function; thereby, decreasing the likelihood of catabolism on the musculature. T2 increases oxygen consumption and oxidative capacity to help speed up the body’s metabolic rate. Increased metabolic rate results in a greater ability to burn fat for energy, causing fat mass declination.
T2 supplementation will lead to increases metabolic rate with the sole purpose of losing fat mass. It does this without shutting down the thyroid gland’s natural functioning while maintaining muscle fiber integrity, and minimizing those negative side effects associated with T3 supplementation. Studies show that in order comparison with T3 supplementation a much greater amount of T2 must be consumed to elicit the same fat burning capacity (one study cited 80x more T2 consumed, compared to that of T3 obtaining the same effect). There isn’t much research concerning the adverse side effects seen in T2. Science has yet to determine whether T2 is safe for human consumption; however, studies have shown that some of the same side effects seen in increased T3 levels, do occur in high levels of T2 as well.