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guy pointing to absHoodia Gordonii is a plant that has been used for many years in South Africa as an appetite suppressant. It was brought to the supplement market in 2004 and served as the next big “diet pill” after ephedra was banned from sale as a weight loss aid. Hoodia Gordonii comes in many forms including capsules, tea, and liquid.

The mechanism of action of Hoodia Gordonii is not fully understood. The appetite suppressant effects of Hoodia Gordonii may be attributed to a constituent of the plant that has been named “P57”. At this time, Hoodia Gordonii is the only plant known to contain this compound. Hoodia Gordonii is often used before meals to avoid overeating. Anecdotal evidence has shown Hoodia Gordonii to be somewhat effective for appetite suppression, although short acting.

Apparently an issue with Hoodia Gordonii supplements is that they often do not meet label claims due to an imbalance between supply and demand of this ingredient. Every company selling Hoodia Gordonii seems to claim that their product is the best, but no one really knows which companies are meeting label claims for their Hoodia Gordonii products.

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3. Iha MH, Trucksess MW, & Tournas VH. (2009). Effect of processing on ochratoxin A content in dried beans. Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment. 26(10), 1389-95.

4. van Heerden FR, Marthinus Horak R, Maharaj VJ, Vleggaar R, Senabe JV, & Gunning PJ. (2007). An appetite suppressant from Hoodia species. Phytochemistry. 68(20), 2545-53.

5. van Heerden FR. (2008). Hoodia gordonii: a natural appetite suppressant. Journal of Ethnopharmacology. 119(3), 434-7.

6. MacLean DB, & Luo LG. (2004). Increased ATP content/production in the hypothalamus may be a signal for energy-sensing of satiety: studies of the anorectic mechanism of a plant steroidal glycoside. Brain Research. 1020(1-2), 1-11.

ABOUT THE AUTHOR: Cassie is a chemistry major and national level bodybuilder. Questions or comments? Talk to Cassie on the FORUM or on FACEBOOK.

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