Not too long ago I summarized a study which evaluated the benefits of combining finasteride with Minoxidil and Finasteride with Ketoconazole. I thought “How dumb, why is there no test group that has all three?” They all have different mechanisms after all. Then I thought “Dutasteride is far superior to finasteride for hair regrowth (30%) but it is way harsher on your erections and it has a 5 week half life. If it makes you impotent you’re going to stay that way for a while.” When reading on topical saw palmetto I thought “It would be better to use dutasteride topically and rub it in to the scalp with the Minoxidil. Thus using all 4 mechanisms: oral Finasteride (F), topical Dutasteride (D), Ketoconazole (K) shampoo every three days and Minoxidil (M) 2 times a day.
Turns out there was a study 4 years ago that proved this works! The 4 fold approach I came up with for hair regrowth works very well! People just thought of it 4 years before I did. In fact, despite the finasteride and the dutasteride being redundant, the 4 products work better than using just the D, M, and K without the F.
I would like to point out something: if you’re on a strong androgen that is a modified DHT like Anavar, Tren, Masteron, Anadrol, or Winstrol, then there is no point in the Finasteride or the Dutasteride since these steroids are already 5 alpha reduced and a 5 Alpha Reductase Inhibitor (5ARI) is pointless for causing hair regrowth or preventing hair loss. A 5ARI will actually decrease neuro hormones used for mood and sex drive. Ideally if you’re just trying to decrease hair loss or cause hair regrowth a topical approach is the way to go.
Aromatase Inhibitors (AI)+ 5ARI when used together were found in one study to INCREASE DHT!!!! Now the sheer stupidity of this study as there was no AI only group (SMH). one group showed that a 5ARI reduced DHT and 5ARI + AI increase DHT up to 10 fold. It would have been common sense to use a AI only group to see if its the AI indirectly boosting the DHT levels. This means if you’re on a 5ARI for the purpose of hair regrowth and you incidentaly get gyno, bloating, moodiness or any other estrogen side effect then implement an AI to reduce estrogen you may cause a huge increase in DHT and MORE hair loss than if you had used nothing for hair loss at all!
Here’s a Thought
If you’re suffering both DHT and estrogen side effects to the point you’re on a 5ARI and a AI maybe the dose is too high? Or you’re using the wrong anabolics? 1-Andro can’t convert to DHT or to estrogen so there is no need for those rescue agents. Its all pros, no cons. Why haven’t you tried it yet?
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