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Men and women lose hair alike as they age. Men more so than women. The process is actually quite complicated but there are 3 different proven medications that can slow, stop, and possibly reverse hair loss.  I will explain hair loss, How each medication works and how science has proven that the use of 2 of them works better than just one, then I will give you a recipe to use all three.

 

Hair Loss

Androgenic Alopecia or male pattern baldness is a very common problem. It used to be believed that you inherit it from your mother’s father aka maternal grandfather but it is a bit more complicated. It is actually an autosomal dominant inheritance with incomplete penetration.  There are 7 stages of hair loss:norwood_avacor_minoxidil_1.gif

 

A study was performed in 2002 which combined different approaches at chemically slowing hair loss.  The first item is most relevant to this website.

 

Finasteride

 

Finasteride trade name Propecia inhibits the 5 alpha reductase enzyme type 2. It inhibits 70% conversion of testosterone to dihydrotestosterone (DHT).  DHT binds to the hair follicles and slowly causes them to die through a complicated method.  For men who use androgenic and anabolic steroids that can convert to DHT finasteride is critical.  Even without the genetic predisposition to hair loss a ton of androgenic steroids can cost anyone their hair. Steroids that are “hardeners” are usually made from DHT and don’t get affected by Finasteride.  Finasteride has a special effect on deca making it MORE androgenic by disallowing its conversion to the weak DHN. For non reducible prohormone that won’t cost you your hair try 1-Androstentalone.

With normal production of testosterone and the 70% reduction of DHT from finasteride 1-4% of men have a loss of sex drive.  Likely their erections suffer as well.  When taking superhuman amounts of testosterone either with steroids or prohormones you shouldn’t have a problem with your sexdrive with finesteride use.  The pathological sexdrive you get as a side effect of testosterone supplementation may be reduced to manageable levels.

 

Minoxidil

 

Minoxidil Is an active ingredient in a shampoo with the most popular brand name of Rogaine.  It nourishes the hair follicle and has been proven to regrow hair from the vertex but not the front of the head. I have however seen before and after pics with dramatic hair regrowth in the front.

 

Ketoconazole

 

Ketoconazole is another active ingredient found in the shampoo Nizoral.  It is an anti fungal which when ingested interferes with the production of androgens. When applied topically acts only on the scalp but does not interfere with other androgen receptors.

 

In the aforementioned study there were 4 tested groups:

Test group 1 received 1 mg Finasteride daily

Test group 2 received 1 mg Finasteride daily and 2% Minoxidil solution 2 times a day

Test group 4 received 1 mg Finasteride daily and 2% Ketoconazol 3 times a week.

Test group 3 received only Minoxidil.

 

I listed group 3 last because it performed terribly. This may be why it only works on vertex baldness, by itself it isn’t as effective as Finasteride alone.

Now the real magic happens when you stack Finasteride.  Finasteride and Minoxidil (Group 2) performed the best and statistically better than minoxidil alone (Group 3), or Finasteride alone (group 1).  Group 2 DID NOT perform STATISTICALLY better than Finasteride and Ketoconazole (group 4).

Here is where it gets weird; Group 4 DID NOT perform STATISTICALLY better than finasteride alone (Group 1).  Do you notice that? 2 is better than 1, but 2 isn’t better than 4 and 4 isn’t better than 1.  Why? because 4s sample size was only 10 people and so any statistics generated with 4 are not statistically significant.  Truth is in the graph, unfortunately I can’t cut and paste it you have to look at the PDF here.

 

So Here Is My Idea

Finasteride is clearly the backbone of the treatment and has a much better solo effect than Minoxidil alone, and if there is a minimal benefit to adding ketoconazole 2 times a week and the best combination is Minoxidil and Finasteride then thats the best protocol is to add the Ketoconazole 3 times a week.  So basically adding 2 to 4 to make 6!

Since all three work on different mechanisms it should work better than just method 2 or 4.

To clarify my recommendation based on this data:

Finasteride 1 mg per day

Minoxidil 2% solution 2 times per day

Ketoconazole 2% solution 3 times per week

 

There is alternative prescription 5-alpha reductase inhibitors to Finasteride.  Dutasteride is way more effective and effects subtype 1 which Finasteride does not.  Your almost guaranteed sexual disfunction with it however.  Alfatradiol is a topical 17 alpha estradiol which won’t bind to the estrogen receptor, but will bind to 5 alpha reductase and deactivate it.

Other natural treatments that are also stackable are ingestion of Reishi mushroom, topical application of saw palmetto and alkalinization of the blood, which everyone should do anyway.

 

References

http://www.karger.com/Article/Fulltext/17954

http://www.dermatol.or.jp/Journal/JD/full/029080489e.pdf

 

Nothing in this article or on this site should be considered medical advice or as an endorsement to violate any law of the country in which you reside.  The information given is for fun and entertainment purposes only.  All claims are 100% dependent upon proper diet and exercise.  Please consult a medical practitioner prior to any diet and exercise program.

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