fit woman exercisingMany alternative treatments for depression have been investigated, including changes in diet, exercise, and the addition of natural supplements. Folate is one nutrient that has been investigated as a possible treatment for those diagnosed with depression. A paper published in the Journal of Phsychopharmacology reviewed 3 studies investigating folate supplementation for treating depression to come to a conclusion regarding the effectiveness of the supplement.

Between the 3 studies, a total of 247 participants were included. Subjective feelings of depression were rated according to the Hamilton Depression Rating Scale. It was found that supplementation with folate decreased subjective feelings of depression enough to be statistically significant, but not enough to be used as a sole treatment for depression.

The researchers concluded that although folate only makes a small difference, it may still be an effective supplement to add to other depression treatment. While folate did appear to be an effective treatment for depression, the folate status of the participants was unknown. In people with sufficient folate levels, supplementation with folate may not be as effective of a treatment as it might be for people with low folate levels.



Taylor MJ, Carney SM, Goodwin GM, & Geddes JR. (2004). Folate for depressive disorders: systematic review and meta-analysis of randomized controlled trials. Journal of Psychopharmacology (Oxford, England). 18(2), 251-6.

ABOUT THE AUTHOR: Cassie is a chemistry major and national level bodybuilder. Questions or comments? Talk to Cassie on the FORUM or on FACEBOOK.

DISCLAIMER: The information on this website reflects the opinion of our staff and manufacturer’s and should not be interpreted as medical advice. The information is not unbiased or independent and is the opinion of the owners of The descriptions and statements accompanying these products and vitamin supplements have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure or prevent any disease.

Lipodrene Hardcore 90CT 25EE wDMAA
someone from Seaford
Total order for 104.85 USD
Liquid Labs T2
someone from Des Moines
Total order for 108.93 USD
someone from Augusta
Total order for 122.98 USD
someone from Dearborn
Total order for 39.98 USD
someone from Anaheim
Total order for 111.94 USD