Wow. What a confusing supplement. Seven years later and there is no clear understanding of this ingredient. It has so many unrelated health benefits it sounds like fish oil. Now we all care about health but lets get real, we want pumps. So I could write 30,000 words explaining the exact pharmacokinetics of every single reported benefit of this popular ingredient but I’m going to focus on the pumps.
Agmatine Enhances Pumps?: Yes or No
Agmatine has the most confusing reputation; It causes increased and decreased NO synthesis. So whats the deal? The deal is that there are 3 types of NOsynthase. That’s the enzyme which converts Arginine to NO. The type in your brain and the type your immune system uses, agmatine inhibits. Thats how it protects your brain and boosts your immune system. The type in your endothelial cells, the cells that line your cappilaries which run through your muscles, it activates. So it boosts NO production in the muscles diverting blood away from your brain and to your muscles. Sounds perfect! Who wants brain activity anyway? When I’m lifting I want to be in the zone and feeling my pump and nothing else.
Agmatine in Pre-Workouts
Lately every pre workout has been throwing agmatine in but that doesn’t really make sense. It needs to be on an empty stomach and takes about 2 weeks to start working. It gives you a perpetual pump, one that lasts all day. NOW you can take Wyked 2.1 pre workout and get an exaggerated effect from the increased NO synthase concentration in the capillaries. Taking Agmatine on an empty first thing in the AM is ideal, like you would DAA. To take advantage of the GH releasing effect it needs to be on an empty stomach anyway.
For this reason I created Rise and Swell. Rise and Swell is the perfect amount of GH releasing secretagogues, Agmatine Sulfate, And DAA to get the best possible results and muscle pumps from your Wyked 2.1 or an inferior pre-workout.
You will not find a better pump than taking rise and swell on an empty stomach first thing in the AM, and Wyked 2.1 pre workout. I made this 1, 2 punch to knock out all the competition.
Nothing in this article or on this site should be considered medical advice or as an endorsement to violate any law of the country in which you reside. The information given is for fun and entertainment purposes only. All claims are 100% dependent upon proper diet and exercise. Please consult a medical practitioner prior to any diet and exercise program.