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Oral Turinabol (OT) is very similar in structure to methandrostenolone. The only difference, in fact, is the addition of a chloride atom at the C-4 position. Oral-turinabol has a reputation of being a very good steroid. The addition of the chloride atom removes the potential for aromatization by blocking access by aromatase and also reduces conversion to DHT. The main differences are that OT likely has a long half-life that makes up for its lower binding affinity and Oral Turinabol seems to have higher affinity for SHBG than methandrostenolone which can result in testosterone and estrogen being bumped into circulation1.

The half-life in the scientific literature after IV administration is 16 hours; however, the oral half-life is not necessarily the same1. Generally half-life for oral administration is longer than that of IV administration, however, in this case it could actually be shorter due to first pass metabolism and reduced peak plasma levels compared to the IV dose1. Another paper suggests a fairly short half-life2. A good estimate is at least eight hours for the half-life of this steroid with the likely true value between 12 and 20 hours. The fact that metabolites of this steroid can be detected for a long time after cessation argues for a longer half-life3.

Users have reported pretty strong suppression of natural testosterone levels while using Oral Turinabol. This steroid is liver toxic but likely only slightly more toxic than equal doses of methandrostenolone. This steroid is well-known for its role in the state-sponsored doping program of the former East German Olympic doping program. This drug was given to male and female athletes specifically to increase athletic performance in the Olympics. Though men were also treated, women were the focus because they responded much better to treatment. Doses of only 10 to 20 mg per day produced marked increases in performance in women. This program also included other drugs like mestanolone, the 11-beta hydroxy form of Oral Turinabol, 4-chloro-methyltestosterone, 4-chloro-mestanolone, methandrostenolone, testosterone and nandrolone esters as well as some stimulants and peptide hormones. Even so, Oral Turinabol was the focus because it seemed to report the best results4.

Oral Turinabol has shown up in recent years on the back market with people using in excess of 100 mg per day. At this dose, one has to wonder if the product contains the correct steroid or is under dosed or if it is just another case of “more is better”.

1.W. Schumann W. [The pharmacokinetics of Oral-Turinabol in humans] Pharmazie. 1991 Sep;46(9):650-4.

2. K. Dürbeck HW, Büker I, Scheulen B, Telin B. GC and capillary column GC/MS determination of synthetic anabolic steroids. II. 4-chloro-methandienone (oral turinabol) and its metabolites. J Chromatogr Sci. 1983 Sep;21(9):405-10.

3. Schanzer W: Metabolism of anabolic androgenic steroids. Clin Chem. Jul;42(7):1001-20, 1996

4. Franke WW, Berendonk B. Hormonal doping and androgenization of athletes: a secret program of the German Democratic Republic government. Clin Chem. 43(7):1262-79, 1997

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