5-Androstenediol, commonly known as 5 AD, may appear under the nomenclature 5-androsten-3b, 17b-diol. 5 AD occurs naturally in the body as a metabolite of DHEA. 5 AD was released early on in the prohormone era, not long after the first prohormone androstenedione. It is very similar in structure to the steroid methandriol, but 5 AD lacks the ester chains at either end of the molecule and the C-17 methyl group that methandriol has.
With an anabolic to androgenic ratio of 10/20, 5 AD is not very anabolically active. It actually has an androgen receptor binding affinity that is even lower than estradiol. 5 AD also has a moderate rate of conversion to estrogen and it may even directly stimulate the estrogen receptor. Users of 5 AD experienced little in the way of actual gains but estrogen related side effects such as gynecomastia were common. Due to its lack of effectiveness and estrogenic side effects, 5 AD lost popularity rapidly. At this point all manufacturers of 5 AD products have discontinued sales of this prohormone.
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[author] [author_image timthumb=’on’]http://www.mindandmuscle.net/articles/wp-content/uploads/2012/04/cassie.jpg[/author_image] [author_info]ABOUT THE AUTHOR: Cassie is a chemistry major and national level bodybuilder. Questions or comments?
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